Predictive Brain

Perception and decision-making are not automatic processes, but strongly shaped by internal brain states, which incorporate our goals, attention, expectations, and knowledge about the world.

The mechanisms by which these “top-down factors” affect perception, cognition, and behavior are still largely unknown. Where do the neuronal top-down signals come from? How do they change communication between sensory and decision-related brain regions? And how do these factors affect our perception and decision-making? These questions are the focus of investigation of our group. We use a combination of behavioural and neuroimaging methods (MEG, fMRI, TMS) in healthy volunteers to examine how percepts and decisions are shaped by what we expect (prediction) and deem relevant (attention).

Key grants and prizes

Key publications

  • Kok P, Jehee JFM & de Lange FP (2012). Less is more: Expectation sharpens representations in the primary visual cortex. Neuron, 75(2), 265–270.
  • Albers AM, Kok P, Toni I, Dijkerman HC & de Lange FP (2013). Shared representations for working memory and mental imagery in early visual cortex. Current Biology, 23(15), 1427–1431.
  • Summerfield C & de Lange FP (2014). Expectation in perceptual decision making: Neural and computational mechanisms. Nature Reviews Neuroscience, 15(11), 745–756.
  • de Lange FP, Heilbron M, Kok P (2018). How do expectations shape perception? Trends in Cognitive Sciences, 22(9), 764-779.
  • Heilbron M, Armeni K, Schoffelen JM, Hagoort P & de Lange FP (2022). A hierarchy of linguistic predictions during natural language comprehension. PNAS, 119(32), e2201968119.

Links

Predictive Brain lab

Research Group
Predictive Brain

Principal Investigator
Prof. Dr. F.P. de Lange

Group members

Postdoctoral Researchers
Dr. Eva Berlot
Dr. Christoph Huber-Huber
Dr. David Richter
Dr. Lea Maria Schmitt
Dr. Eelke Spaak
Dr. Yamil Vidal
Dr. Britta Westner
Dr. Ingmar de Vries
Dr. Mandy Bartsch

PhD's
Kevin van den Berg
Floortje Bouwkamp
Ilayda Nazli
Maartje Koot
Qifei Wang

Research Assistant
Virag Fodor

MSc and BSc Students
Aarti Ramchandran
Inés Schönmann
Tristan Meijers

*Open group photo (jpg, 146 kB)

Contact information

024-3610651
Postal address
Postbus 9101
6500HB NIJMEGEN